Seroepidemiology of Toxoplasma gondii Infection among Pregnant Women in Public Hospital in Khoy, Northwest of Iran, 2015–2017

Document Type : Original Article

Authors

1 Department of Parasitology, Faculty of Medical Sciences and Health Services Khoy, Urmia,

2 Department of Parasitology, School of Medicine, Kashan University of Medical Sciences, Kashan

3 Department of Parasitology, Urmia University of Medical Sciences, Urmia, Iran

10.4103/iahs.iahs_7_17

Abstract

Aims: Toxoplasma gondii is a protozoan parasite and congenital transmission, abortion, and prenatal mortality are major problems of this
parasite. This study was carried out to determine the seroprevalence of Toxoplasma infection in the pregnant women, referring to Khoy Public
Hospital, Iran, during 2015–2017. Materials and Methods: In this descriptive cross‑sectional study, 3 ml of venous blood were taken from
1060 pregnant women and centrifuged; the collected sera were kept in a freezer at - 20°C until testing. Then, samples were examined for the
presence of IgG and IgM Toxoplasma antibodies using Autobio ELISA kit according to manufacturer’s instructions. Data analysis was done
using Chi‑square test and SPSS‑10 software. Results: Among 1060 serum samples of pregnant women, 38.2% were positive for anti‑T. gondii
antibodies. IgG and IgM titers of antibodies to T. gondii were positive in 36.6% and 1.2% of women, respectively. The incidence in women
older than 30 years was 49.3%. The positive rate of IgG of pregnant women increased with age (P < 0.05). In women who were living in the
village, the prevalence was 45.5% and in urban women, it was 21.5%; this difference was statistically significant (P < 0.05). Conclusion: The
relatively high prevalence of T. gondii infection in this study showed that pregnant women infected with this parasite at an early age and it is
important for pregnant women to prevent irreversible complications in neonates.

Keywords